Jefe de Departamento
Investigador Titular (Cinvestav 3-C) Doctor en Ciencias (Bioquímica, 1989)
CINVESTAV.
Temas de investigación:
Regulación de la concentración intracelular de calcio en células de
músculo liso. Mecanismos moleculares de la muerte celular o apoptosis inducida por
calcio. Regulación del calcio intracelular y de la actividad de la bomba de calcio
SERCA en estados de resistencia a la insulina, estrés del retículo
endoplásmico y la diabetes.
Más información...
Membresía del SNI: Nivel II
Teléfono: (52) (55) 5747-3950
Fax: (52) (55) 5747-3391
Correo-E:
aguerrero@cinvestav.mx
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García-Rivas G.J.,
Guerrero-Hernández, A., Guerrero-Serna, G., Rodríguez-Zavala,
J.S. and Zazueta, C. Inhibition of the mitochondrial calcium uniporter by the
oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents
from irreversible injury in postischemic rat heart. FEBS J.
272 (2005) 3477. |
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Gómez-Viquez, L., Rueda, A.,
García, U., Guerrero-Hernández, A. Complex effects of
ryanodine on the sarcoplasmic reticulum Ca2+ levels in smooth muscle
cells. Cell Calcium. 38 (2005) 121. |
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Leticia Gómez-Viquez, Guadalupe
Guerrero-Serna, Ubaldo García and Agustín Guerrero-Hernández.
SERCA pump optimizes Ca2+ release by a mechanism independent of store
filling in smooth muscle cells. Biophysical Journal. (2003) 85:370-380.
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Beatriz Aguilar-Maldonado, Leticia
Gómez-Viquez, Lucía García, Rosa M. Del Angel, José
Antonio Arias-Montaño and Agustín Guerrero-Hernández.
Histamine potentiates IP3-mediated Ca2+ release via
thapsigargin-sensitive Ca2+ pumps. Cellular Signalling.
(2003) 15: 689-697. |
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Agustín
Guerrero-Hernández, Leticia Gómez-Viquez, Guadalupe Guerrero-Serna
and Angélica Rueda. Ryanodine receptors in smooth muscle. Frontiers in
Bioscience. (2002) 7:d1676-1688. |
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Angélica Rueda, Lucía
García, Luis Enrique Soria-Jasso, José Antonio Arias-Montaño
and Agustín Guerrero-Hernández. The initial inositol (1,4,5)
trisphosphate response induced by histamine is strongly amplified by Ca2+
release from internal stores in smooth muscle. Cell Calcium. (2002)
31:161-173. |
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Angélica Rueda, Lucía
García, and Agustín Guerrero-Hernández. Luminal
Ca2+ and the activity of sarcoplasmic reticulum Ca2+ pumps
modulate histamine-induced all-or-none Ca2+ release in smooth muscle
cells. Cellular Signalling. (2002) 14:517-527. |
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Agustín Guerrero and
Juan Manuel Arias. Capítulo 68 "Apoptosis" en Cell Physiology Sourcebook,
A Molecular Approach, 3ra. ed. editado por Nicholas Sperelakis, Academic Press.
(2001) pp 1171-1184. |
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Michael T. Kirber, Agustín
Guerrero-Hernández, Douglas S. Bowman, Kevin Fogarty, Richard A. Tuft,
Joshua J. Singer and Frederic S. Fay. Multiple pathways responsible for the
stretch-induced increase in calcium concentration in toad stomach smooth muscle
cells. Journal of Physiology. (2000) 524:3-17. |
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Gutierrez, A.A., Arias, J.M.,
García, L., Mas-Oliva, J. and Guerrero, A. Activation of
Ca2+ permeable cation channel by two different inducers of apoptosis
in a human prostatic cancer cell line. J. Physiol. (1999) 517:95. |
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Agustín Guerrero and
Juan Manuel Arias. Capítulo 67 "Apoptosis" en Cell Physiology Source
Book, 2da. ed. editado por Nicholas Sperelakis, Academic Press (1998) pp
1031-1043. |
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Guerrero, A., García,
L., Zapata, O., Rodríguez, E. and Darszon, A. Acrosome reaction inactivation
in sea urchin sperm. Biochim. Biophys. Acta (1998) 1401:329. |
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Muñoz, A., García,
L. and Guerrero-Hernández, A. In situ characterization of the
Ca2+ sensitivity of large conductance Ca2+-activated K+
channels: Implications for their use as near-membrane Ca2+ indicators
in smooth muscle cells. Biophys. J. (1998) 75:1774. |
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Agustín Guerrero,
Joshua J. Singer and Fredric S. Fay. Simultaneous measurement of Ca2+
release and influx into smooth muscle cells in response to caffeine. A novel
approach for calculating the fraction of current carried by calcium. Journal
of General Physiology. (1994) 104:395-422. |
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Agustín Guerrero,
Fredric S. Fay and Joshua J. Singer. Caffeine activates a Ca2+
permeable, nonselective cation channel in smooth muscle cells. Journal of
General Physiology. (1994) 104:375-394. |
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Le Xu, Anthony Lai, Anita Cohn,
Elaine Etter, Agustín Guerrero, Fredric S. Fay and Gerhard Meissner.
Evidence for a Ca2+-gated ryanodine-sensitive Ca2+ release
channel in visceral smooth muscle. Proceedings of the National Academy of
Sciences, USA. (1994) 91:3294-3298. |
PRINCIPAL
PLANTA ACADÉMICA
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